Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.
The goal of translational development at Celgene (CITRE) is to provide a team that is fully integrated both with our discovery efforts and clinical development. To enable this, Translational Development will engage with discovery project teams to support target selection and disease area strategies, provide leadership for early clinical programmes from CD nomination to proof of principle (i.e., Phase 2A) studies.
In order to facilitate this, Translational Development will be integrated into Early Development Teams that will cost effectively and rapidly move the portfolio through early safety, efficacy and signal searching studies and ultimately hand over provide a robust roadmap for registration to the late development or Brand Teams. The Translational Development group is responsible for working with discovery to develop target validation approaches, define appropriate disease models for clinical studies, early engagement with discovery and early development team for biomarker maker development, defining patient selection strategies, and clinical pharmacology to define starting doses and schedules for dose escalation in Phase 1 studies.
In addition, rational design of combination of novel molecules which challenge the current treatment paradigms will be encouraged. There is a close working relationship with toxicology
As part of Celgene’s commitment to scientific excellence and research in Europe, we have established the Centre for Translational Research in Europe (CITRE) in Sevilla. The aim of this centre is to be the European Hub for our BioBanking, Bioinformatics and Early Phase Clinical Trials. In addition, we are aiming to develop facilities for stem progenitor cell research. These will complement our early research facilities in San Diego, San Francisco and Summit NJ. We are seeking to help gifted scientific with a proven track record in academia or industry to create this unique installation and deliver an ambitious program for the rapid and efficient delivery of Celgene’s portfolio in Oncology, Inflammation, Immunology and Cell Therapies.
To deliver key translational studies to project teams supporting overall goals of translational development
Responsibilities include the following:
Not ready to apply?Join Our Talent Network
Celgene is a global biopharmaceutical company committed to improving the lives of patients worldwide. At Celgene, we seek to deliver truly innovative and life-changing treatments for our patients.